Summary: The risks associated with the use of laboratory chemicals must be well understood prior to their use in an experiment. As many chemicals have multiple hazards, ensure to review the safety guidance for all hazard classes that may apply.

Definition:
Reproductive toxins are substances that adversely affect reproductive capabilities, including chromosomal damage (mutagens). Developmental toxins are substances that adversely affect the embryo or fetus.

IMPORTANT: Lab personnel should recognize that many chemicals have not been thoroughly assessed for their reproductive toxicity. Prior to selecting/ using chemicals in the laboratory, researchers should determine their potential reproductive toxicity risks.

Reproductive Toxins List:
Under CA Proposition 65, the State of California maintains a list of known chemicals causing reproductive toxicity. For the updated list, refer to: http://www.oehha.ca.gov/prop65/prop65_list/Newlist.html#files

Examples:
Chemicals that are reproductive or developmental hazards include: Ethylene dibromide, dibromochloropropane, arsenic, mercury compounds.

Stanford University’s Reproductive & Developmental Health Protection Program:
Personnel planning to use reproductive toxins can get more health-related information and further consultation via: http://www.stanford.edu/dept/EHS/prod/mainrencon/occhealth/Reproductive/.